ACANTHOSIS NIGRICANS is characterized by hyperpigmented, verrucous, or velvety plaque which usually appears on flexural surfaces and in intertriginous regions.

Commonly seen in individuals with insulin resistance states, especially obesity, and less frequently in association with other metabolic disorders, drugs, and malignancy.

It is usually an indication of underline hormonal imbalance.

The management of patients generally starts with taking a detailed history to rule out other causes, physical examination, and a set of laboratory investigations.


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